An EU Expert Committee recently produced a manual on the Community Regulatory Framework for Medical Devices to clarify uncertainty surrounding certain borderline Medical Devices. In this document, they ruled that ‘blood storage refrigerators, freezers and defrosters sold for the specific intended purpose of dealing with blood should be medical devices in their own right’. This has since been under consideration in the UK by the MHRA who have indicated acceptance of this determination and so regulation is imminent to ensure that all new blood banks in the UK are manufactured in compliance with the new rules.

The impact of these changes on UK Blood Transfusion users is yet to become clear. Potential advantages are the reassurance that these products are designed and manufactured in accordance with detailed and exacting standards; the manufacturers, their procedures and documentation are independently audited on a regular basis; and a standardised set of safety criteria are applied across all Medical Devices. However, in view of the considerable research and development required to gain Medical Device certification for each product it is inevitable that all manufacturers and suppliers will need to review what products they continue to offer. There are also likely to be conditions and restrictions placed on users of such equipment in order to ensure continued compliance with Medical Device standards.

At Labcold, having kept abreast of developments in the EU, we have long anticipated that this decision was only a matter of time - particularly in view of the MHRA’s earlier ruling in 2007 that Platelet Agitators are Medical Devices. Labcold, as the UK’s largest manufacturer, already holds ISO 13485 accreditation as a Medical Devices Manufacturer, allowing us to respond quickly to this latest development and already all Labcold Blood Bank refrigerators and Platelet Agitators are certified Class IIa Medical Devices as defined by MDD93/42/EEC ANNEX V. It is expected that the Labcold range of plasma freezers will share this endorsement shortly. We believe that Labcold is currently the only company in Europe to be in this position.

How this new ruling is to be regulated and enforced is still very much in the hands of the MHRA and Labcold is seeking meetings with them to clarify their thinking to ensure we are in the position to give our customers the most accurate and up-to-date advice and information.

So, in order for professionals to be confident the blood bank they purchase will be a certified medical device as laid down by the EU and soon to be rigorously enforced by the MHRA, Labcold’s British built models are probably the only ones on the market now that can be guaranteed to meet, and even exceed these regulatory requirements.

Labcold is pleased to announce that from the 1st December 2008 a Technical Service Manager, Allan Dickhart will be added to their growing service team. This means that expert technical assistance will now only be a phone call away for all customers, especially those who take advantage of Labcold’s competitive and comprehensive warranty and maintenance agreements.

As the complexity of the Labcold range increases, particularly with the recent certification of Labcold blood banks as medical devices, providing a front-line fix plus sound installation and maintenance advice has never been so important. Allan, with a proven track record in both technical engineering and running a busy service department will be the ideal person to deliver this service, improving customer response time considerably with his diagnostic and managerial skills.

But, this is not the only improvement Labcold is planning for its service department. Labcold completely understands that good after sales advice is vital if their equipment is to meet customer expectations. All members of the department have already been on a comprehensive meeting customer needs training course, but Labcold won’t be content to stop there. As well as investing in people, it will be upgrading the service software to ensure that Labcold continues to be ideally placed to meet the exciting challenges provided by the demands of being the largest UK based manufacturer of medical and scientific refrigeration products.

LEARNING FROM HUMAN NATURE - Safe vaccine storage with Labcold refrigerators

LABCOLD LAUNCHES COMPLETELY NEW RANGE OF PHARMACY REFRIGERATORS AT 2008 PHARMACY SHOW

LABCOLD KEEPS EVERYTHING COOL FOR PRINCESS ROYAL - British manufacturer supplies all refrigeration needs for state-of-the-art oncology institute

FRIDGE OVER TROUBLED WATER, ‘Spark-Free’ Labcold Raises Safety Awareness

Inappropriate refrigerators, often domestic designs, used in laboratories have been the cause of potentially fatal explosions over the years. Minimising the risk of fire, therefore, through appropriate handling and storage of any potentially flammable materials, as well as the installation of proper electrical equipment, is of paramount importance within the medical, laboratory and scientific sectors.

Addressing the issue head-on, creating an all-round safer working environment, is the UK’s leading specialist manufacturer of professional laboratory refrigeration equipment, Labcold. With over 40 years experience in the supply of temperature control products for scientific and medical use, the company introduced one of the first ever ‘spark-free’ refrigerators.
Robin Gregson, Sales & Marketing Director at Labcold, explains the innovation: “The Labcold range was designed so there is no possible point of ignition internally; having remote sensing temperature controllers and no internal switches, heaters or lights inside, removes all electrical contacts to the outside of the chamber. Our products therefore are intrinsically safe in this regard, hence there has never been a single reported instance of a Labcold unit causing a fire
anywhere in the world.”

Sadly, that same safety element does not apply to most domestic-type products, still in use at many scientific establishments, despite the horror stories that occasionally hit the headlines. Domestic appliances usually contain fairly simple devices, including low-tech internal thermostats as well as an internal light and the door switch to operate it - all of which can cause a spark. This presents a huge risk of any flammable vapours igniting when in normal operation and also to personnel even when simply opening and closing a door. Labcold’s spark-free range, including a novel high-performance fan circulated, model demonstrates the company’s innovative approach to product development and ongoing commitment to establishing a safer workplace. The fan circulated spark-free model uses an externally mounted motor, driving the fan blades via a shaft that passes into the spark-free chamber.

“Fridges, particularly large ones, have poor temperature uniformity if they do not have some form of forced air circulation,” adds Robin, “But normally the installation of a fan renders the inside non spark-free. Our model has excellent temperature control characteristics and is also completely safe.”
Labcold’s comprehensive product portfolio includes chest and front-loading models in varying sizes with a host of safety features such as lockable doors and temperature alarms.

THE ICE IS RIGHT, Cube Or Flake? The only decision to make

The new Labcold-ITV icemakers offer optimum performance together with a practical and stylish design from an award-winning, international market leader.
Both the Ice Maker “flake” and Ice Maker “cube” versions are low maintenance and available in a variety of sizes for use in laboratories and medical facilities.  Elegantly constructed from stainless steel, the exterior is robust, yet aesthetically pleasing to the eye and is surprisingly compact in size, particularly the LITVIQ135 model, which occupies very little floor space.  Internally, the ice storage and collection bins are manufactured from strong foam plastic materials, ensuring excellent thermal insulation.

The FLAKE version produces flakes that are extremely regular in size and suitably soft making them ideal for medical applications, as the flakes mould around the surface of items to be cooled, as well as providing optimum heat exchange – moreover, the softness makes it easy for test tube insertions, as well as orthopaedic applications to the human body.

The alternative CUBE icemaker actually produces cylindrical shaped ice, each cylinder being approximately 40g.  The unique spray system that produces the ice features a patented design spray nozzle, fabricated from a flexible, semi-elastic material, which counteracts the build up of any limescale.

Free from delicate electronics, and constructed from high quality materials with great attention to ease of maintenance, these icemakers are among the most robust, easy to use and reliable in the business.
 
Labcold’s optional installation and commissioning service at extra cost is highly recommended to ensure correct usage and reliable operation.

The 2008 Labcold Product Catalogue is packed full of new and inventive ideas

UK specialist manufacturer of scientific and medical refrigerators & freezers LABCOLD has just published the new edition of its ever-popular catalogue.  The essential guide provides full information on LABCOLD products, as well as details on all new ranges, plus improved specifications and designs.

This year’s product innovations include:

• The fully revised range of UK manufactured Labcold ADVANCED refrigerators and freezers, offering improved performance in a stylish package
• Ice Makers (Cube, Flake & Crushed) – A new range from major Spanish manufacturer ITV
• Temperature Mapping, Validation, Monitoring & Recording – A full range of products and services to ensure that equipment is operating correctly
• Blood Banks – Already recognised as the market leader, Labcold has completely redesigned its Blood Bank Refrigerators and the control systems to be fully compliant to latest MHRA requirements

Labcold’s Michelle Rogers sums up the significance of the 2008 catalogue:

“We make so many improvements to our products and additions to the range throughout the year that having the latest edition of our catalogue ensures you keep up to date.  Customers get updates on our whole product portfolio, new design specifications and access to advice on selection of the right equipment, as well as the requirements of various standards and guidelines.” 

The catalogue also contains a Product Selection Guide and a Glossary of Terms, to help customers find the right products for their needs.

Ammonia – The Best Cooling Solution?

Safety scare at The O2 highlights risks.

Last month (Oct 07), 30 staff members at The O2 arena in Greenwich, South London, had to be taken to hospital following a leak of ammonia from the site's ice rink cooling system. This incident highlights the need for managers and specifiers to be aware of the risks as well as the benefits of using ammonia-based refrigeration.

For sound engineering reasons due to its physical properties ammonia is commonly used in industrial cooling plant, but it is also present in some smaller fridges designed for use in doctors' surgeries and hospital treatment rooms. The risk of leakages of this poisonous gas from the use of ammonia absorbtion technology have been reported on numerous occasions including incidents in Perth during 2004, during 2005 in South Wales and more recently at both Edinburgh University and a West Lothian health centre. In each case a minor leak has resulted in major consequences including evacuation of buildings, attendance of emergency services and affected personnel being treated in hospital.

Martin Slatford, who is responsible for Health and Safety at industry-leading professional refrigeration firm Labcold, says: “Ammonia has been used in refrigeration systems for over 150 years, but there can be circumstances where it may pose a health and safety risk to staff and patients. When selecting refrigeration equipment, it is important to check how it will be used and where it will be located. For example, will it be in a non-ventilated small space such as a doctor's surgery? “While ammonia-based systems are quiet and cheap to manufacture, the potential risks to health and safety must not be ignored,” he continued.

Labcold strongly recommends that before purchasing ammonia-based appliances purchasers should seek expert advice or better still err on the side of caution by selecting non-poisonous refrigerant gases. The Labcold range of refrigerators is ammonia and CFC-free.

Pharmacy And Practice Fridges Must Be Green Book Compliant For Safe Vaccine And Pharmaceutical Storage

133 children in Scotland were recalled and re-vaccinated during 2007 because the original vaccines administered were potentially inactive due to incorrect storage temperature.  Such incidents highlight the importance of the new Department of Health (DoH) Green Book requirements on vaccine refrigeration.  Concerned Pharmacy Managers can rest easy with Labcold professional fridges and freezers. 

All Labcold pharmacy products are fully compliant with the new DoH Green Book as well as Royal Pharmaceutical Society of Great Britain (RPSGB) Guidelines.  Key issues raised by these include the calibration, monitoring and validation of an even temperature throughout the storage chamber.  Failure to ensure this, and to be able to demonstrate that correct temperatures have been maintained, leaves medical professionals at risk of dispensing unlicensed medicines.  The DoH Green Book also clearly states that domestic fridges are no longer acceptable for storage of vaccines.  What’s more, Labcold can offer advice to pharmacy managers on likely future requirements – for example the next issue of the RPSGB Guidelines are expected to call for separate storage and dispense fridges.

The revised Labcold range of Pharmacy Refrigerators, includes new glass-door 285 and 150 litre models to complement the existing highly popular solid door range.

Labcold refrigerators are already widely used in both chain and independent pharmacies and were chosen for the successful high-street Chlamydia screening service pilot undertaken by the Department of Health at over 200 London pharmacies.

“At present, hospitals and pharmacies are working to guidelines in which the inclusion of alarms that will alert staff if the temperature in a medical or scientific refrigerator rises or falls below set ranges is only a recommendation, not a requirement. But all laboratory, pharmacy and hospital managers should assess which of their refrigerators are likely to store crucial, highly temperature-critical materials and choose models with alarms. It's better to be safe than sorry,” said Martin Slatford, in charge of Health & Safety at Labcold.

‘Holby City’ Plotline Should Set Alarms Ringing For Hospital, Pharmacy And Laboratory Managers

A plotline from the popular BBC1 TV drama 'Holby City' has urgent vital safety lessons for the medical and scientific communities, says Robin Gregson, Sales and Marketing Director of Labcold.
In the long-running storyline, a vital medical implant is rendered dangerous when an over-zealous employee on the look-out for carbon savings decides to turn off the refrigerator in which it was being stored, as she thought it was empty. Unfortunately, no-one notices the error until it is too late and a patient suffers as a result.
“This really emphasises the crucial importance of using specially designed, installed and maintained refrigeration equipment for sensitive medical and scientific uses,” said Robin.
“Ironically, the appliance featured on the programme was a Labcold model which has an audible alarm which will go off if the temperature rises or falls past set limits, even if the unit is unplugged. But showing that would not have made for such good drama!”
In one recent UK incident, 133 children were recalled and re-vaccinated because the original vaccines that were administered were potentially inactive, due to having been stored in a part of the fridge chamber where the temperature was too low (even though the fridge thermometer was apparently reading the correct temperature). This suggests the use of an inappropriately designed fridge, lack of calibration or a malfunction.

Another example happened in Multnomah County, Oregon in the United States where between 2003 and 2006 more than 6,500 people were given a vaccine that was improperly refrigerated and may have been ineffective. The problem was due to staff not monitoring the temperatures within refrigerators used for vaccine storage. As a result, the local health authority has replaced all the fridges – which were domestic models – with professional pharmaceutical refrigerators equipped with computerised temperature measurement. These set off audible alarms, both in the clinics and at a central office, should the temperatures vary from standard.
“At present, hospitals and pharmacies are working to guidelines in which the inclusion of alarms that will alert staff if the temperature in a medical or scientific refrigerator rises or falls below set ranges is only a recommendation, not a requirement. But all laboratory, pharmacy and hospital managers should assess which of their refrigerators are likely to store crucial, highly temperaturecritical materials and choose models with alarms. It's better to be safe than sorry,” added Robin.

High Flyer Joins Labcold

Steven Moore has joined the sales team of specialist refrigeration manufacturer Labcold to provide support to equipment re-sellers in the North of England and Scotland. Based in Manchester, Steven will assist distributors in all aspects of developing the sales of Labcold products.

Prior to his career in Scientific Sales, Steven, a Biology Graduate from Stockport, had three years in retail sales followed by five years as a Medical Laboratory Scientist working in the Manchester and South Lancashire area.
One of the UK’s leading competitors and instructors in the world of flying model fast jet airplanes, Steven says he needs similar skills in serving Labcold’s customers. “These model jets aren’t like conventional model aircraft,” he explained. “They can reach speeds of up to 300mph, requiring fast reactions and absolute concentration – skills I intend to bring to my dealings with our customers!”

Robin Gregson, Sales & Marketing Director at Labcold, said, “This new appointment reflects the
recent massive increase in sales through our rapidly growing network of re-sellers as well as the growing popularity of Labcold products.”

Pharmacy Show: Labcold Offers Free Refrigerated Storage Compliance Check

Pharmacy managers concerned about the impact of the new Department of Health (DoH) Green Book requirements on vaccine refrigeration will find the answers to all their questions on the Labcold stand at this year’s Pharmacy Show.
Following a successful debut at last year’s show, Labcold will be featuring its revised range of Pharmacy Refrigerators, including an all-new glass-door 285 Litre model.  The glass door line-up will also include 140 litre and 360 litre models to complement the existing highly popular solid door range.

All products are fully compliant with the new DoH Green Book on storage of vaccines as well as Royal Pharmaceutical Society of Great Britain (RPSGB) Guidelines.  Key issues raised by these include the calibration, monitoring and validation of an even temperature throughout the storage chamber - none of which can be met by the domestic refrigerators currently in wide use by many pharmacies. Labcold estimates that over 50,000 pharmacy refrigerators will need to be replaced.

Labcold experts will be on hand to offer advice to pharmacy managers on the requirements of the new guidelines and on likely future enhancements – for example, the next issue of the RPSGB Guidelines are expected to call for separate storage and dispense fridges.

Labcold refrigerators are already widely used in both chain and independent pharmacies and were chosen for the high-street Chlamydia screening service pilot undertaken by the Department of Health at over 200 London pharmacies.

Robin Gregson, Sales & Marketing Director at Labcold, said: “These new models have been designed and developed in response to the needs of our customers.  When pharmacies start to upgrade their refrigerated storage facilities, we believe our new range will be unbeatable in the market.”

Vaccine Storage

Make sure that your medical refrigeration meets current and future standards, advises Robin Gregson.

The increasing challenge surrounding the storage of vaccines and pharmaceuticals by primary care practices and pharmacies has been reinforced by the publication of the health department’s Green Book guidelines. In the past, it has been common to store products requiring refrigerated temperatures in simple domestic fridges with limited, if any, monitoring of actual storage temperatures, and without any calibration of the equipment. In an increasingly regulated, not to mention litigious, society there is an urgent need for healthcare professionals involved in the storage of vaccines and pharmaceuticals to take appropriate action.

In one recent incident widely reported in the press, 133 children had to be recalled and revaccinated. The original vaccines that they were administered were potentially inactive due to having been stored in a part of the fridge chamber where the temperature was too low (even though the fridge thermometer was apparently reading the correct temperature). This suggests the use of an inappropriately designed fridge, lack of calibration or a malfunction.

Awareness and guidelines

Even once awareness has been raised of how important the correct type of refrigeration is, there is plenty of paperwork to wade through before those who must act can feel fully informed on this topic. The health department’s Green Book on Immunisation is the exemplar of such paperwork. It provides detailed guidance and may be seen as enhancing the existing Royal Pharmaceutical Society of Great Britain guidelines.

Whilst many diligent practice managers are doing their best to cope with the additional demand on their time that the question of vaccine and pharmaceutical storage presents, these documents do not necessarily provide clear and simple instructions on exactly what action to take. With so many other priorities, often more pressing, it is not surprising that the matter can be put aside or wrong decisions made. It is, after all, in the very nature of ‘guidelines’ that they allow scope for interpretation.

However, help is at hand. One UK manufacturer has been closely monitoring developments in refrigeration storage in GP practices and has already assisted many of its customers in achieving compliance with guidelines. Labcold provides a range of solutions covering all medical storage needs – products that are designed to meet both current and anticipated requirements.

Labcold has long supplied fridges conforming to the previous (1996) Green Book and also RPSGB guidelines, so the company is well placed to keep up with the latest changes. As market leader and the UK’s largest manufacturer in an even more tightly controlled application – namely, blood storage refrigerators – Labcold is also well versed in the way that requirements and guidelines are likely to develop.

Labcold provides a range of solutions covering all medical storage needs – products that are designed to meet both current and anticipated requirements. Click here to see the full range.

Labcold Cytotherm Thaws Plasma Rapidly Without Risk Of Cross-Contamination

The risks of cross-contamination during thawing of frozen plasma are becoming well know to blood transfusion professionals.  This can be of particular concern with traditional wet methods such as water baths.  Some of the newer thawing methods introduced have either taken unacceptably long or have run the risk of overheating the plasma with potentially disastrous consequences.

The unique indirect warm water technique, with ‘massaging’ action of the Labcold Cytotherm rapid plasma thawing unit enhances the speed and efficiency of thawing to avoid this risk.  As a result, sales of the unit are increasing as hospital staff discover the benefits and reassurance it brings.

The Cytotherm also incorporates other important safety features, including:
· Robust replaceable plastic bladders that contain the warm water used for heating and maintain a barrier against cross contamination
· Alarm and cut-out in the event of a leaking plasma pack
· Water temperature closely controlled to 37^OC plus or minus 0.1^OC, with alarm and cut-out, eliminates possibility of overheating the plasma
· Dual independent operation with containment of spillages

Robin Gregson, Sales & Marketing Director at Labcold, said, “This unit is proving very popular due to the speed of operation combined with the inbuilt safety features”

Labcold Offers Wide Range Of Flake & Cube Ice-Makers

Labcold has an ice-making solution for every routine laboratory situation – ice flakes or ice cubes – from extremely compact units for use where space is limited to higher volume models producing up to 165 kg per day.

All models have a compact design, stainless steel exterior, automatic operation and fail-safe features.  Once correctly installed and commissioned the icemakers will deliver reliable operation over a long life.

Click here to read in detail about the two ranges.

New Equipment Range Helps Keep Medical

Labcold has introduced a new range of portable refrigerators and temperature loggers to ensure the safe transport of temperature-sensitive medical and blood products and samples.

There are two portable refrigerator models in the new range.  One is specially designed to transport blood products and samples, so is factory set to +4°C, plus or minus 2°C. The second is for general medical use and can also act as an incubator, with an adjustable temperature range of -5°C to +60°C.  Both models are lightweight yet robust, and are unaffected by tipping or vibration. They operate on 12 or 240V and are free of CFCs, HCFCs and ammonia.

The portable temperature loggers are small, lightweight, self-contained units that sense and record temperature data for later download to a PC.  Two types are available, both able to measure temperatures across a wide range to an accuracy of plus or minus 0.5°C.

Robin Gregson, Sales & Marketing Director at Labcold, said: “As well as blood, it is increasingly important to ensure that many other medical and pharmaceutical products and samples are kept at a closely controlled and monitored temperature.  This is especially difficult outside the controlled conditions of a laboratory or medical facility so our range has been designed to provide a complete, easy to use solution.”

Name Change for Borolabs Ltd

Labcold^TM Exhibiting at The Pharmacy Show for the First Time.

Reflecting increasing sales to the sector, LABCOLD^TM is a first-time exhibitor at the 2007 Pharmacy Show being held at the NEC on 15 &16 October. Already a well-established supplier to high street chain and independent pharmacies as well as surgery-based/hospital-based dispensaries, the company is exhibiting in order to promote its range more widely.

LABCOLD^TM is a government approved supplier of vaccine and pharmaceutical storage refrigerators to hospitals and the armed forces. First choice for many PFI projects, the company was chosen to supply 200 refrigerators for the London pilot of the High Street Chlamydia Testing service.

The full LABCOLD^TM range, in sizes from 35 to 1245 litres, conforms to RPSGB guidelines and is available from all leading distributors.

LABCOLD^TM has just published a special version of its catalogue for use by Pharmacists and Practice Managers, covering only the products of interest to them. It is printed in a handy format that can be opened out and used as a reference chart. LABCOLD^TM Sales and Marketing Director Robin Gregson said, "We wanted to make it really easy for Pharmacists and Practice Managers to find the products they need, so produced this special excerpt from our comprehensive main catalogue."

LABCOLD^TM is an independent British company, recognised as the UK's leading specialist manufacturer of professional Refrigerators and Freezers for use in scientific, laboratory and medical applications.

It's just a fridge, isn't it?

Robin Gregson, Sales & Marketing Director of Labcold^TM, gives advice on choosing a pharmacy refrigerator.

Q: When is a fridge not a fridge?

A: When it's a pharmacy refrigerator.

Of course, they both keep things cool. But one can be a mass-produced "cheap and cheerful" product sold on the high street or out-of-town retail parks, while the other is a crucial piece of medical equipment.

Domestic fridges have to meet the strict guidelines on keeping food fresh, but these are different to those needed to preserve vaccines and not as exacting. Specialist medical refrigerators designed for pharmacy use are designed and manufactured to maintain vaccines, pharmaceuticals, samples and other critical medical products at a closely controlled, carefully monitored temperature.

While domestic fridges can be designed to meet the changing whims of fashion, those for scientific and medical uses have rather more important criteria to consider - performance, safety and reliability are key factors. One important difference is that, in a medical refrigerator, the temperature needs to be within the specified range throughout the chamber and not just in one place.

Cold air is, of course, more dense than warm. As a result it naturally sinks to the bottom of the refrigerator chamber, resulting in a temperature gradient. Spatial temperature variation is an important consideration when designing a pharmacy refrigerator.

Another vital factor is how the refrigerator operates to maintain an operating temperature within tight parameters. Most systems use electric motors to compress the refrigerant gas into a liquid which in turn is allowed to evaporate, so cooling the chamber. This process cannot be switched off and on as rapidly as a heater, and there is also a degree of "overshoot" or "undershoot" inherent in the gas/liquid transition. The result is a temperature fluctuation throughout the chamber on a regular basis. Further complications arise if - as in many medical and pharmacy applications - the refrigerator door is opened on a regular basis, unlike most domestic uses.

Careful attention to system design, microprocessor control systems and higher specification materials can all mitigate against this fluctation.

Of course, if anything does go wrong it can be a disaster for those whose work depends on the samples and pharmaceuticals contained within. So the refrigerator should be specified with at least a local alarm. They should also have a storage space which is designed for the purpose, with flexible shelving options according to the exact needs of each individual user. Locks will also help in ensuring that only authorised personnel can access the contents.

Just like buying a domestic fridge, users should look for models which are CFC and HCFC free, and choose the most energy efficient model wherever possible.

Another danger which is often overlooked is the risk of ammonia leaks. There is a long history of incidents involving leaks of this poisonous gas from some refrigerators used in medical and pharmacy applications where they employ ammonia as a refrigerant. Here buyers should choose ammonia-free machines with more benign refrigerants that should ideally be inert and minimise damage to the environment. So, having decided on the specifications required, how do you go about choosing the brand of refrigerator or freezer? Of course, it is tempting to choose a familiar "high street brand" best known for producing domestic versions. But there are specialist manufacturers who concentrate all their knowledge and expertise into producing models specifically designed for medical, scientific and laboratory use.

Whoever you choose, an idea is to select one from a knowledgeable supplier, with sales staff able to discuss and advise you on the best options. The supplier should be able to advise not just on meeting current requirements, such as those issued by the vaccine manufacturers and the Royal Pharmaceutical Society of Great Britain's Code of Ethics and Standards, but also on forthcoming legislation or directives to provide a degree of "future proofing". The supplier should also be able to keep you up to date with the best practice.

Best also perhaps to choose a manufacturer that is amongst the market leaders in high-end, critical applications such as blood banks and spark-free technology.

A final point to consider is whether the refrigerators are available in the right size to suit the user - space is often very limited so an ideal range will include bench-top units and medium under-bench models as well as the larger free-standing ones. There are even models available that can be mounted on the wall.

For over 40 years, the Labcold^TM range has been the first choice for scientific, laboratory and medical use. A leading chain of high street chemists ordered over 200 for their Chlamydia Testing Service while hundreds of independent pharmacies and GP/PCT surgeries use them for pharmaceutical and vaccine storage. What's more, a growing list of PFI hospitals have specified the Labcold^TM range based on the company's unsurpassed specialist experience and expertise. Finally, Labcold^TM products are listed and approved for supply against government contracts reflecting the company's position as a key supplier to NHS and private hospitals for many years.

The Labcold^TM range is readily available ex-stock from a wide range of partner suppliers with whom Labcold^TM works closely to provide expert support and advice for medical and scientific users. Of course, you could still choose to buy this important piece of medical equipment from that pleasant young man doing his Saturday job in the discount electrical warehouse...

Four New Product Ranges Featured Updated LABCOLD^TM Catalogue

LABCOLD^TM has just published a new updated edition of its popular catalogue detailing four completely new product ranges as well as full information and specifications on all products.

The new product ranges are:

• Portable Refrigerators - Two versions - One for the transport of blood products and one for samples, vaccines and pharmaceuticals.
• Portable Temperature Loggers - A selection of products designed to assist in compliance with the EU Blood Directive.
• Flake and Cube Icemakers - With a choice of 8 models.
• The Cytotherm Rapid Plasma Thawer - an easy to use unit that keeps plasma packs dry.

Sales and Marketing Director Robin Gregson said, "With the introduction of so many new products every year, having the latest edition of our catalogue ensures you keep up to date - not just with the product range and specifications, but also with the advice on selection of the right equipment plus the requirements of various standards and guidelines"

The catalogue also contains a Product Selection Guide and a Glossary of Terms to help customers find the right products of their needs.

"Customers tell us that they find it a very useful reference" added Robin.

Advanced Fridges and Freezers from Borolabs

Borolabs announces the launch of a new range of advanced fridges and freezers for the most demanding applications in pharmaceutical and biotechnology laboratories.

All products display a wider range of operating temperatures than most conventional fridges and freezers. The fridges range from an extremely low temperature of -5°C to 12°C, while the freezers can be set for temperatures as low as -26°C. Accurate and stable temperatures are achieved due to the sophisticated microprocessor control and fan air circulation. All feature automatic defrosting so that in normal use the cabinets do not have to be taken out of commission for defrosting.

A multifunction alarm system has been fitted as standard. The audio and visual alerts are triggered due to unacceptable temperature changes and there are contacts for remote alarms, should they be required as part of laboratory protocol.

The fridges and freezers are constructed with either stainless steel or white ABS interiors and there is a glass door option on all models to allow contents to be checked without affecting temperatures.

Lab Fridge Freezers - the Perfect Combination

Labcold^TM fridge freezers provide the ultimate in space saving and convenience while offering a choice of solutions to suit a variety of applications. Borolabs has introduced these combined cabinets in either sparkfree or advanced models.

The advanced model is designed for extremely accurate temperature control, while the spark-free models provide maximum safety for mixed laboratory products. All three cabinets in the range offer refrigerators with automatic defrosting, while in the spark-free models the freezer section can be defrosted while the fridges operate normally. Both chambers can be independently controlled for further flexibility. A multi-function alarm system is fitted as standard to the advanced fridge/freezer.

No Sparks Fly with Borolabs

Official figures show that fires in laboratories caused by fridges are many times more common than those in the home. However, in the 20 years since Borolabs introduced the Labcold range there has not been one reported incident with any of their models.

Now, due to customer demand, Borolabs introduces two new mid-range sparkfree refrigerators with capacities of 142 and 215 litres. Both models incorporate all the features of existing products in the range including automatic defrosting and lockable doors.

The refrigerators have been designed so there is no possible point of ignition. Remote sensing temperature controllers take all electrical contacts outside the chamber. The new models use the off cycle system for automatic defrosting and so do not need heaters which would cause ignition.

Economy Models Retain Quality Features

Recognising the need for a reliable, large capacity fridge and freezer at the lowest price possible, a new Economy range has been launched by Borolabs.

The refrigerator and freezer have capacities of 505 litres and the tough metal interiors can withstand the most rigorous everyday use. The refrigerator has adjustable shelves for greater flexibility, with the shelves of the freezer being fixed and refrigerated. Both have door locks and temperature displays fixed to the exterior control panel. Defrost control for the freezer is operator controlled, while the refrigerator uses a microprocessor timed off cycle system to provide maximum sample protection during defrosting.

The freezer has been designed to make it particularly suitable for enzyme storage. The operator-controlled defrosting and refrigerated shelves provide the stable temperature environment required.

Brochure on New Healthcare Range Available From Borolabs

Borolabs announces the availability of a new full colour brochure covering the Labcold range of products dedicated to the Healthcare market.

The Healthcare brochure details blood banks, platelet systems, plasma freezers, portable refrigerators and freezers and units dedicated to pharmacy applications - all suitable for temperature control in Healthcare.

The brochure is available now by directly contacting Borolabs on 01256 347049, or by e-mail at brochure@borolabs.co.uk. Catalogues on complementary products are also available.

Labcold^TM Finds Strength For the `Pharmacy`

Borolabs, the specialist in temperature control and monitoring solutions, has launched a range of Labcold^TM refrigerators and freezers dedicated to the needs of pharmacists who want reliable performance from robust and safe units.

The 'Pharmacy' range achieves accurate temperatures using integrated microprocessor control, with levels maintained constantly throughout the inner chambers using fan assisted air circulation. With the needs of the pharmacist in mind, the units are robustly constructed with white stainless steel exteriors and easy to clean interiors. An automatic defrosting facility reduces temperature fluctuations and ensures maximum efficiency through low maintenance.

The models are compatible with Labcold^TM Central Monitoring Systems to automatically monitor running operations and connections are provided to access remote alarms and management systems for total security protection.

Other features include a user-friendly digital display, with code protection; lockable castors, for easy positioning; fully adjustable shelves, for storage flexibility and optional glass doors.

A full colour brochure, covering all Healthcare products, can be obtained from Borolabs on 01256 347049, or by e-mail at brochure@borolabs.co.uk.

Shaking Platelets Until the Doors Open

Expanding its Healthcare^TM products, Borolabs, the specialists in temperature control and monitoring solutions, has unveiled a range of robust and safe incubators for the optimum storage of platelets in the blood transfusion laboratory.

The 'Platelet' range of incubators are constructed with robust, easy to clean exteriors and interiors to cope with busy transfusion centres. Platelet storage at 22ºC in an active state ensures their optimum use. Users can be assured of reaching and maintaining such accurate storage temperatures with the 'Platelet' range, even in the warmest of laboratory conditions, thanks to advanced microprocessor control.

Gently shaking platelets has also been shown to maximise their useful life by minimising the effects of clumping. Accordingly, the Platelet incubators have been designed to operate with a range of agitators, also available from Borolabs. For additional safety, and advanced models have power to the agitator is automatically shut off when the cabinet door is opened.

An integrated Intelligent Labcold Blood Monitor alarm keeps a constant check on the normal operating conditions of the incubator to warn users of abnormal temperature deviations, power failures, or if the door is left open too long. A seven day temperature recorder allows management staff to keep a permanent record of operations and connections are also provided to access remote alarm devices for sample security.

With lockable castors available on the floor standing models and adjustable feet on the bench top models, the Platelet system range from Borolabs can be easily positioned to suit the needs of the laboratory.

A full colour brochure, covering all Healthcare products, can be obtained from Borolabs on 01256 347049, or by e-mail at brochure@borolabs.co.uk. Catalogues on complementary products, such as Monitoring and Alarms, are also available.

EDITORS NOTES Platelets are tiny, sticky cells found in blood that clump together to help prevent bleeding after a sudden wound. Platelet transfusions have been shown to benefit patients suffering bone marrow failures, post transplant and chemotherapy treatments and also leukemia, so keeping a ready supply of platelets under optimum conditions for immediate use is vital.

Labcold^TM Gives Plasma the Chill Without the Spill

Borolabs, the specialists in temperature control and monitoring solutions, is responding to the demands of busy hospitals and clinics by launching a range of freezers for practical and affordable storage of blood plasma products.

The Labcold^TM Plasma freezers provide safe storage of blood products in compliance with BS4376 (1996) Part 2 and the 'Guidelines for the Blood Transfusion Service'. In doing so the Labcold system has been shown to significantly reduce bag cracking and provides rapid thaw times.

The Plasma freezers are constructed with tough exteriors in a compact upright design that occupies a reduced floor area. Three easy pull out drawers, with cold retaining fronts, stabilise interior temperatures and extra thick insulation around the chamber reduces power consumption.

An intelligent alarm system provides a continuous multifunction check on cabinet performance. Abnormal temperatures, power supply failures, or leaving the cabinet door open for too long will trigger audible and visual warnings. Connections are available to centralised alarm devices for complete sample security and a lockable door provides further security.

A built-in tamper free temperature recorder produces a permanent and continuous record of freezer operations. This operates from an independent power source for complete reliability.

EDITORS NOTES Plasma is the fluid that carries blood cells and other components around the body. Fresh frozen plasma is used where conditions become threatening as a result of heavy blood loss, during cardiac surgery or following childbirth, for example. Consequently, it is of vital importance to emergency support units to hold sufficient stocks in safe and reliable storage for rapid use.

Putting the Labcold^TM on Freezer Fires

Borolabs, the specialist in temperature control, alerts laboratory staff to the use of well designed safe and secure freezers to guard against the possible dangers from explosion and fires through the low temperature storage of flammable chemicals.

Domestic freezers are unsuitable for use in laboratories. They include sources of ignition which can ignite solvents and flammable vapours, causing damage to the building and laboratory staff. In one particular incident, a freezer fire destroyed an entire chemical laboratory and adjacent offices. According to accident investigators, a spark from the arching of an internal air circulation fan, used in the freezer design, probably ignited flammable vapours that escaped from the broken seal of a stored ether compound. Fortunately, no one was injured from the incident.

For this reason, Borolabs has designed a range of Labcold^TM freezers with spark-free interiors. All potentially hazardous electrical contacts are moved outside the chamber to be replaced by remote sensing temperature controllers. For additional safety, interior lights and air circulation fans are omitted from the design and efficient door gaskets avoid the need for electrically heated strips around the door.

There are literally thousands of Labcold spark free freezers and refrigerators around the world and there is no record of any fire or explosion caused by any one of them. Chest and front loading models are available in a range of sizes with a host of safety features including lockable lids and temperature alarms.

A leaflet entitled 'Top Tips on How to Avoid Lab Fires' can be obtained by contacting Borolabs on 01256 347049.

No Nuisance With Borolabs

The new 'Advanced' range of refrigerators and freezers from Borolabs provides users with a comprehensive range of features to ensure outstanding performance and reliability. The units are robustly constructed and can be tailor made to suit a variety of applications.

All models in the Advanced range achieve accurate temperatures through microprocessor control. Temperature circulation is optimised throughout the inner chambers by fan-assisted air circulation. This feature switches off automatically, in all but the smallest models, for additional safety when the door is left open.

Users can be assured that valuable contents are protected by an integrated multifunctional alarm that continuously monitors daily functions. The alarm alerts of any unacceptable changes, but avoids 'nuisance' warnings through a time delay feature, ensuring that only the most urgent alarms are sounded for immediate attention.

The 'Advanced' units can be tailor-made to suit a variety of settings, from the laboratory to manufacturing. Internal power outlets and access ports allow the operation of equipment inside the chambers and a range of accessories such as special shelving, drawers, racks and scaffolding permit a variety of layout options.

All models are constructed with white exteriors and stainless steel or white ABS interiors for robust handling and are rated for operation in the warmest of environments. The units should also never be out of commission, thanks to an automatic defrosting feature that ensures optimum operating performance.

Other features include lockable castors for easy positioning; clear digital displays for easy set up; a code protection facility to safeguard important functions and optional glass doors.

Take to the Road with Labcold^TM

For those who need sophisticated refrigeration power found in the laboratory but want the freedom to travel then the latest range of portable Labcold^TM Carritherm refrigerators and freezers, from Borolabs, are ideal. These units provide sophisticated refrigeration power in a tough lightweight construction for easy transit.

Considerable cooling power is achieved in the Carritherm models using a heavy duty compressor refrigeration system that pumps environmentally friendly refrigerant round a sealed system. This means that chamber temperatures can be selected down to -20ªC even when operating in high ambient conditions. Interiors in the lightweight units are also cooled by a large surface area metal evaporator which is similar to that used in laboratory refrigerators.

All the models can operate on 12 volt DC battery power for reliable mains free operation out in the field. Once back in the laboratory, the units can operate from mains power, with the three larger models able to connect directly without the need for a mains adapter. A range of models are available: from the smallest at 13 litre capacity, right up to a 62 litre model. All are strongly constructed with smooth durable exteriors and also feature microprocessor control, for temperature accuracy with clear digital displays. Larger models have side handles and the smallest one features a shoulder strap for carrying.

Borolabs Takes Monitoring to the Max

Safeguarding perishable items by continuously monitoring the normal operation of laboratory equipment is a vital requirement. Over the years, Borolabs, the specialist in temperature control, has supplied monitoring solutions to hospitals, pharmaceutical and water companies and the food and beverage industry. Now the company unveils the Monitor Max, as the latest convenient way of confirming, recording and analysing temperatures and other parameters in a variety of laboratory equipment.

The Standard Monitor Max Command unit can monitor up to 16 items of equipment, which can increase to up to 96 items using optional Expansion Modules. This means that an entire building can be monitored from a single Monitor Max system. To fulfil this requirement, longer probe cables can be used with complete confidence that the signal integrity will remain in tact, thanks to improvements in two wire technology.

Consistent and accurate temperature readings are achieved using the latest platinum resistance thermometers. Monitor Max covers a temperature range from -200ºC to +150ºC at a resolution accuracy of 0.1ºC. The unit achieves this using two internal probes so that a wide range of equipment, including refrigerators, freezers and incubators can be monitored simultaneously.

For peace of mind, all points have sufficient memory to store over 35,000 readings, which is over one years' history at 15 minute intervals. If users want the information to be converted to P.C. formatted records, then data can be can be downloaded from the Monitor Max using an optional Windows Data Analysis Software package, available from Borolabs. This system also provides the freedom and convenience from off site management. Authorised staff can check all monitored equipment, download data or change settings at the Monitor Max using a modem from their own P.C, regardless of their station locality.

Security is an important issue addressed by Borolabs in the manufacture of Monitor Max. All critical settings are password protected and any changes made are logged in the units' memory. Monitor Max is able to provide continuous equipment monitoring even when mains power to the unit fails. At this point integrated self charging batteries take over and trigger audible warnings to alert users of the change in circumstances. Warnings also sound if the wiring or probes are damaged in any way, offering total equipment protection.

Operating and programming the Monitor Max is intuitive with the large liquid crystal display provided. The system is designed for easy installation using low voltage network wiring, and can work with any make of equipment in the laboratory. Borolabs also provides a comprehensive customer service policy to offer before and after sales advice. Accredited engineers are available to install, validate, calibrate and service all the products to ensure that customers achieve the best performance from the Monitor Max, and other products available from Borolabs.

Labheat Refrigerated Incubators Take the Heat Out of Inaccurate Temperature Control

Labheat^TM refrigerated incubators from Borolabs, the specialists in temperature control and monitoring solutions, allow users to choose operating temperatures independent of the room environment. The latest range offers a number of features that combine operational accuracy with reliability, flexibility and ease of use.

The Labheat refrigerated incubators use an exclusive electronic control system to achieve a temperature precision to within +0.1ºC over 0 to 50ºC range. Fan air circulation also helps maintain stable temperatures throughout the incubator. Dual temperature cycling is an optional feature that allows users to set two individual incubation temperatures for repeat cycling or delayed starts to incubation periods.

There are standard and advanced models available, including a cost effective 260 litre model and a spacious 1112 litre unit. This particular model is ideal for large scale shelf life testing, from food to biotech and pharmaceutical industry needs.

All models are designed with robust exteriors and easy to clean interiors. Other specifications include tamper proof digital temperature settings, glass or lockable solid doors and optional access ports for temperature monitoring systems.

Advanced units are also available with internal power supplies, inner doors and timed inner illumination control. Borolabs can also produce cabinets to house temperature sensitive tests or other apparatus according to customer requirements.

Electronic Protection for Labcold^TM

Borolabs, the specialists in temperature control and monitoring solutions, is responding to customer needs once more by introducing a unique versatile electronic door locking facility onto many of its Labcold^TM refrigerators and freezers. The locks are password protected for authorised access and also feature automatic locking for total security.

Security is particularly important when holding valuable perishable items, such as pharmaceutical products or blood stocks. The unique electronic lock automatically locks the door after access. A short delay allows re-entry if required, but ensures maximum security in even the busiest environment.

Ordinary keys tend to get lost or break. With the electronic door locks, authorised users enter their pin number on the integrated keypad to release the door. This accessibility is important for equipment such as Blood Banks, which are in continuous 24 hour use.

Borolabs can also interface the electronic locks with sophisticated systems that recognise valid swipe cards or bar-codes to offer customers a range of door locking options.

New BS Blood Banks Safeguard Blood Stocks

The storage of blood stocks in reliable blood banks is vital for busy transfusion departments. Borolabs today announces a new range of BS Blood Banks that comply fully with strict BS4376 (1991) part 1 standards for system design and performance. Part of the renowned Labcold^TM range, these robust units guard against the splitting of blood packs, through efficient temperature control. Other features include dual independent refrigeration, a novel text display Blood Monitor alarm, digital electronic door locking, and a choice of sizes and drawer or shelving options.

Reliability and security were vital design considerations. Dual independent refrigeration on larger models, as recommended by the British Standard, ensures operation efficiency in high ambient temperatures and independent servicing so the blood banks are never out of action. Electronic door locking, on solid door models, operates automatically for security during busy use, and a suitable interface will allow magnetic swipe card and bar code control access for future flexibility. Operating conditions are checked continuously and users alerted if blood packs are not stored under optimum conditions by a text display 'Blood Monitor' system, developed by Borolabs.

Borolabs have supplied high quality Labcold blood banks to hospitals, clinics and UK military forces for over 20 years, and this new range forms part of the latest generation of reliable and innovative cabinets, which are produced in a range of sizes and specifications to suit every application.

All Labcold^TM Blood Banks Great and Small

Borolabs announces the availability of a new full colour brochure covering the Labcold range of products dedicated to the Healthcare market.

The Healthcare brochure details blood banks, platelet systems, plasma freezers, portable refrigerators and freezers and units dedicated to pharmacy applications - all suitable for temperature control in Healthcare.

The brochure is available now by directly contacting Borolabs on 01256 347049, or by e-mail at brochure@borolabs.co.uk. Catalogues on complementary products are also available.

New Agent in Ireland Strengthens Labcold Network

The Labcold range of refrigerators, freezers, blood banks and pharmacy refrigerators will now be sold exclusively throughout Ireland by Isis. The appointment was made by UK manufacturers of Labcold products, Borolabs.

Based in Bray, Co. Wicklow, Isis has particular expertise in the Irish healthcare market and the experience and commitment of its sales people has already seen results for Borolabs.

"We are looking forward to a long and successful relationship." says Robin Gregson, Sales director at Borolabs. "Everyone from Isis working on our account has been given full training and we believe our products fill an important niche in the Irish healthcare and laboratory industries."

Space Age Technology Transports Labcold^TM Blood Banks

The new portable Labcold^TM Blood Bank, from Borolabs, incorporates advanced insulation technology, developed for NASA, for the temporary storage and reliable transfer of blood products. This unit is ideal for emergency use at remote sites or home treatment. It is light weight, easy to clean, operates from 12 volt d.c or mains power, and the temperature control complies fully with BS4376 (1991) Part 1.

At the heart of the portable Blood Bank unit is a solid state Peltier system to ensure storage temperatures at 4ºC. Fan assisted air-circulation also helps stabilise the inner temperature throughout during use.

An independent alarm system gives a clear ACCEPT or REJECT notification on the safety of the blood products stored in the portable unit, which provides vital assurances in emergency situations. Temperature performance is automatically recorded, and users can download this information to their computer using the free software utility from Borolabs.

Other features include a hinged or removable lid, a convenient fold out tray for standing blood packs on, an easy to read digital temperature display, and a folding carry handle for easy transport. Labcold^TM has been a major supplier of blood banks for over 20 years and this new portable range further enhances its reputation as leaders in the field.

Borolabs Stays Cool Over Extended Warranty

Peace of mind is no longer a luxury for laboratories wanting to ensure that their samples are safe and protected in laboratory fridges and freezers. In a move to ensure customers obtain the most reliable laboratory products, Borolabs now offers an extended three year warranty on most models in its Labcold^TM product range of refrigerators and freezers. This new deal covers parts and labour. Borolabs has installed literally hundreds of models in many blue-chip establishments throughout the country. It is the company's confidence in its products, based on the fact that so many Labcold^TM fridges and freezers have been reliably operating for a long time, that allows this new warranty to be offered for only a small premium.

Borolabs is the largest specialist manufacturer of refrigerators, freezers, incubators and accessories in the UK. Labcold^TM units in particular are renowned for their robust build quality and reliable performance. With over 70 years in the business, the company combines engineering expertise with full customer support from an experienced team based in Aldermaston.

New Labcold^TM Freezers Outclass Domestic Models

Borolabs, the temperature control specialists, is responding to industry demands once more with a new range of Labcold^TM spark-free freezers that operate at temperatures lower than many domestic freezers currently on the market.

Ruggedly constructed for busy laboratory use, the new LabcoldTM spark-free freezers operate reliably down to -25ºC temperatures, even in high ambient environments. Spark-free interiors in particular provide the best protection for samples and stocks. Borolabs has replaced many of the heat and spark hazards found in domestic units with efficient door gaskets and remote temperature sensing devices for total safety.

The defrosting system is completely operator controlled and all models feature either lockable lids on chest models, or optional lockable doors on front opening models for sample security. Chest models in particular are economical to run. An extra cooling section has been included for the rapid freezing of new stocks, and a Labcold^TM filing system helps organise enzymes and samples for efficient long term storage.

A Hot Solution for Measuring Environmental Impact

With environmental issues at the forefront of the political agenda once more, one way to assess man's impact is to monitor the affects of pollution on ecosystems and habitats. Today, scientists use Bioassay techniques to study growth and genotoxicity in organisms such as simple marine life.

Offering a novel testing service to clients, a new UK start-up company has recently invested in the latest reliable, efficient incubators from Borolabs to culture simple marine embryos for bioassays. The results of such tests are used to reveal the level of contamination from strategic locations around the UK coastline, and also to understand the underlying mechanisms of toxicity.

Coastal & Marine Biotechnologies (CMB) Ltd is an independent company that undertakes expert, confidential and impartial research & development in marine environmental impact assessment, bio-monitoring and cryogenic research. Formed in December 2000, the company decided to equip its new testing facilities with incubators from Borolabs because of the company's reputation, and the quality of products and services available.

Borolabs is the UK's leading supplier of temperature controlling units for the laboratory. Accurate and extremely reliable, the company's Labheat laboratory incubators are popular with commercial and research establishments nationwide, large or small.

Labheat incubators are chosen because of their robust, reliable build design, and accurate temperature control. Features throughout the range include efficient fan air circulation, Borolabs own devised electronic control systems, hard-wearing exteriors, easy to clean interiors, self-sealing magnetic door gaskets, lockable solid doors and eye level temperature displays. The Labheat range covers analogue, digital, large volume, carbon-dioxide and refrigerated models.

Borolabs also supply monitoring systems such as temperature recorders, alarm systems, data loggers and sophisticated telephone dial out units for total security. "The fact that such an important laboratory chose our incubators over other manufacturers is a significant boost," says Robin Gregson, Borolabs' Sales and Marketing Director. "We specialise in fitting out laboratories for scientific and healthcare companies, multi-national organisations, and hospitals. By offering this level of expertise to start-up companies like CMB means we can see the potential for future growth, and make the most reliable temperature controlling solutions available to any laboratory wanting to protect their valuable samples and products."

"We looked at a wide range of solutions available on the market, but none matched the level of specification and capability we required. As well as building units that are robust and reliable, the company is competitive on price. The whole package is ideal for the type of work we do, " explains John Wedderburn from CMB. CMB has built a reputation on providing expertise in marine shell fish and finfish bio-monitoring, Research & Development and other specialist services. A suite of internationally recognised bioassay techniques and in-house protocols are on offer.

Biomarker techniques in particular can be used to determine biological effect, enabling cellular, physiological, and reproductive responses to be quantified in diverse organisms. Genotoxic measures of environmental damage can be determined in conjunction with conventional bioassays, and CMB carries out a range of bioassays on mussel and oyster embryos. Bioassay techniques, used to provide the data for such information, are standard, highly sensitive procedures used to measure factors such as the effects of ambient pollution. In a typical bioassay, water samples are collected from a test site, then brought back to the laboratory where they are inoculated with fresh oyster eggs or mussel eggs. The inoculated samples are then incubated in a carefully controlled environment for a designated period, after which the samples are preserved in formalin for microscope analysis. What laboratory analysts are looking for is poor shell morphology, abnormal development or even embryo death which could mean the test samples came from a source contaminated with high levels of substances, such as hydrocarbons, that have a detrimental effect on marine growth. To ensure result integrity, CMB runs the bioassay with controls and recognised standards, and controls confounding factors such as temperature and salinity that could affect embryo development. Since the growing shell fish larvae have to be maintained at stable, critical temperatures, it is vital to use accurate and reliable incubators when handling valuable samples. In these Bioassay tests, Pacific oysters need to be maintained at 25ºC for 24 hours, whilst mussels need to be maintained at 15ºC for 48 hours. This is one of reasons why CMB chose Labheat incubators.

Borolabs engineers were also on hand to modify the incubator units according to the specific needs of CMB's laboratory. Furthermore, Borolabs installed their temperature monitoring equipment with the units so that laboratory staff at CMB could keep daily checks of incubator performance and provide clients with a permanent record of the temperature environment used to incubate the growing larvae.

Already, CMB has landed significant contracts from Governmental departments, EU funded programmes, multinational companies, universities and agencies, and won prestigious awards for its services. Unlike other companies in its field, CMB has the ability to cryopreserve embryo samples. This means marine shellfish samples can be stored at differing stages of development, then thawed and used in a standard bioassay. This gives CMB greater freedom to perform tests whenever clients require them, and means the technique can be used in more responsive modes when results are needed quickly. This capability is of interest to DEFRA and the UK Government's national marine monitoring programme. During such operations, samples are collected from strategic test sites around the UK coastline. This is a huge logistical undertaking, and conditions on board ship are not always conducive to accurate sample testing. A land-based laboratory, where conditions can be carefully controlled, is always a preffered option. This is where CMB's cryopreservation facility comes in, and will allow DEFRA to conduct its marine monitoring programme in a more accurate and cost effective manner than ever before.

From the outset, CMB has made a significant investment in terms of the skills and laboratory equipment. The company is on the verge of expanding its operations and aims to develop three laboratories - one for the cryogenic processing and storage of bio-samples, a wet lab for sample handling, and a 'clean' area for processing and imaging. Whatever the future plans, CMB is certain to consider Borolabs once more as a key supplier of quality, reliable laboratory units as it continues to grow and provide a bio-monitoring service that is second to none.